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KMID : 0604020120270040230
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Korean Journal of Critical Care Medicine
2012 Volume.27 No. 4 p.230 ~ p.236
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Gender Differences in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention
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Han Suk-Won
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Abstract
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Background: Limited data are available for gender-based differences among patients with acute myocardial infarction (AMI) undergoing coronary revascularization in Korea. The purpose of this study is to identify gender-based differences in clinical characteristics, risk factors and outcomes among Korean patients undergoing percutaneous coronary intervention (PCI).
Methods: Patients with AMI undergoing PCI between Jan 2009 and Sep 2011 were included (n = 457) in the study. Clinical characteristics and cardiovascular risk factors as well as major adverse cardiac events (MACE), including death after PCI, were compared between women (n = 134) and men (n = 323).
Results: Women were older (69.8 ± 10.7 vs. 60.0 ± 11.7 years, p ＜ .001) and had more comorbidities, such as diabetes (44.0% vs. 32.8%, p = .025) and hypertension (64.9% vs. 48.9%, p = .002) compared to men. Women were less likely to have a smoking history (p ＜ .001). There were no significant differences in all causes of death and in MACE between women and men. By the multivariate analysis, age, HDL-cholesterol and left ventricle ejection fraction are associated with mortality and MACE.
Conclusions: In this study, women did not emerge as an independent predictor for MACE; however, they were older and had a higher incidence of hypertension and diabetes than men.
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KEYWORD
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angioplasty, comorbidity, gender, mortality, myocardial infarction
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